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Desarrollo embrionario del pelo (página 5)


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60. Lorenzo EM. Familial study of hirsutism. J Clin Endocrinol

1970 31:556-564

61. Mahoudeau JA, Bardin CW, Lipsett MB. The metabolic

clearance rate and origin of plasma dihydrotestosterone in

man and its conversion to the 5a-androstenediols. J Clin

Invest 1971 50:1338-1344

62. Marugo M, Bernasconi D, Meozzi M, Del Monte P, Zino V,

Primarolo P, Badaracco B. The use of flutamide in the

management of hirsutism. J Endocrinol Invest 1994 17:195-199

Revista de Endocrinología Ginecológica y Reproductiva 17

63. Mathur RS, Moody LO, Landgrebe S, Williamson HO. Plasma

a n d rogens and sex hormone binding globulin in the

evaluation of hirsute females. Fertil Steril 1981 35:29-35

64. Mauvais-Jarvis P. Regulation of androgen receptor and 5-

reductase in the skin of normal and hirsute women. Clin

Endocrinol Metab 1986 15:307-317

65. McKenna TJ, Miller RB, Liddle GW. Plasma pregnenolone

and 17-OH pregnenolone in patients with adrenal tumors,

ACTH excess, or idiopathic hirsutism. J Clin Endocrinol

Metab 1977 44:231-236

66. Mehta A, Matwijiw I, Taylor PJ, Salamon EA, Kredentser JV,

Faiman C. Should androgen levels be measured in hirsute

women with normal menstrual cycles? Int J Fertil 1992 37:354-357

67. Meikle AW, Odell WD. Effect of short and long-term

dexamethasone on 3a-androstanediol glucuronide in hirsute

women. Fertil Steril 1986 46:227-231

68. Mowszowicz I, Melanitou E, Doukani A, Wright F, Kuttenn F,

Mauvais-Jarvis P. Androgen binding capacity and 5areductase

activity in pubic skin fibroblasts from hirsute

patients. J Clin Endocrinol Metab 1983 56:1209-1213

69. Müderris II, Bayram F, Sahin Y, Kelestimur F, Tutus A, Ayata

D. The efficacy of 250 mg/day flutamide in the treatment of

patients with hirsutism. Fertil Steril 1996 66:220-222

70. O"Brien RC, Cooper ME, Murray RML, Seeman E, Thomas AK,

Jerums G. Comparison of sequential cypro t e rone acetate/

e s t rogen vs. spironolactone/oral contraceptive in the tre a t m e n t

of hirsutism. J Clin Endocrinol Metab 1991 72:1008-1013

71. Oh HS, Smart RC. An estrogen receptor pathway regulates

the telogen anagen hair follicle transition and influences

epidermal cell proliferation. Proc Natl Acad Sci USA 1996

93:12525-12530

72. Pang S, Wang M, Jeffries S, Riddick L, Clark A, Estrada E.

Normal and elevated 3a-androstanediol glucuro n i d e

concentrations in women with various causes of hirsutism

and its correlation with degree of hirsutism and androgen

levels. J Clin Endocrinol Metab 1992 75:243-48

73. Paoletti A, Cagnacci A, Orru M, Ajossa S, Guerriero S, Melis

G. Treatment with flutamide improves hyperinsulinemia in

women with idiopathic hirsutism. Fertil Steril 1999 72(3):448-453

74. Paoletti AM, Cagnacci A, Orru M, Ajossa S, Guerriero S, Melis

GB. Treatment with flutamide improves hyperinsulinemia in

women with idiopathic hirsutism. Fertil Steril 1999 72:448-453

75. Paulson RJ, Serafini PC, Catalino JA, Lobo RA. Measurements

of 3a, 17 b-androstanediol glucuronide in serum and urine

and the correlation with skin 5a-reductase activity. Fertil

Steril 1996 46:222-226

76. Philpott MP, Sanders DA, Kealey T. Effects of insulin and

insulin-like growth factors on cultured human hair follicles:

IGF-1 at physiologic concentrations is an important regulator of

hair follicle growth in vitro. J Invest Dermatol 1994 102:857-861

77. Pittaway DE, Maxson WS, Wentz AC. Spironolactone in

combination drug therapy for unresponsive hirsutism. Fertil

Steril 1985 43: 878-882

78. Pugeat M, Forest M, Nisula B, Corniau, De Pere t t i ,

Tourniaire. Evidence of excessive androgen secretion by

both the ovary and the adrenal in patients with idiopathic

hirsutism. Obstet Gynecol 1982 59:46-51

79. Randall VA. Androgens and human hair growth. Clin

Endocrinol 1994 (Oxf) 40:439-457

80. Rittmaster RS, Thompson DL. Effect of leuprolide and

dexamethasone on hair growth and hormone levels in

hirsute women: the relative importance of the ovary and the

adrenal in the pathogenesis of hirsutism. J Clin Endocrinol

Metab 1990 70:1096-1102

81. Rittmaster RS. Androgen conjugates: physiology and clinical

significance. Endocr Rev 1993 14:121-132

82. Rittmaster RS. Finasteride. N Engl J Med 1994 330:120-125

83. San Millan JL, Sancho J, Calvo RM. Role of pentanucleotide

(TTTTA) polymorphism in the promoter of the CYP11 gene

in the pathogenesis of hirsutism. Fertil Steril 2001 75(4):797-802

84. Sawaya ME, Price VH. Different levels of 5 a-reductase type

I and II, aromatase, and androgen receptor in hair follicles

of women and men with androgenetic alopecia. J Invest

Dermatol 1997 109:296-300

85. Sawaya ME, Shalita AR. Androgen receptor polymorphisms

(CAG repeat lengths) in androgenetic alopecia, hirsutism

and acne. J Cutan Med Surg 1998 3:9-15

86. Serafini P, Lobo RA. Increased 5a-reductase activity in

idiopathic hirsutism. Fertil Steril 1985 43:74-78

87. Serafini P, Lobo RA. The effects of spironolactone on adre n a l

s t e roidogenesis in hirsute women. Fertil Steril 1985 44:595-599

88. Stenn, Paus, Filippi. Letter to the Editor. J Invest Dermatol

1998 110:95

8 9 . Tartagni M, Schonauer L, De Salvia M, Cicinelli E, De

P e rgola G, D"Addario V. Comparison of Diane 35 and

Diane 35 plus finasteride in the treatment of hirsutism 2000

7 3 ( 4 ) : 7 1 8 – 7 2 3

90. Thigpen AE, Silver RI, Guilleyard JM, Casey ML, McConnell

JD, Russell DW. Tissue distribution and ontogeny of steroid

5-reductase isoenzyme expression. J Clin Invest 1993 92:903-

910

91. Thomas JP, Oake RJ. Androgen metabolism in the skin of

hirsute women. J Clin Endocrinol Metab 1974 38:19-22

92. Tolino A, Petrone A, Sarnacchiaro F, Cirillo D, Ronsini S,

Lombardi G, Nappi C. Finasteride in the treatment of

hirsutism: new therapeutic perspectives. Fertil Steril 1996 66:61-65

93. Venturoli S, Marescalchi O, Colombo FM, Macrelli S, Ravaioli

B, Bagnoli A, Paradisi R, Flamigni C. A pro s p e c t i v e

randomized trial comparing low dose flutamide, finasteride,

ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism. J Clin Endocrinol Metab 1999 84:1304-1310

94. Vermeulen A, Stoica T, Verdonck L. The apparent free testosterone concentration, an index of androgenicity. J Clin

Endocrinol 1971 33:759-767

95. Vottero A, Stratakis C, Ghizzoni L, Longui C, Karl M, Chrousos G. Androgen Receptor-Mediated Hypersensitivity

to Androgens in Women with Nonhyperandro g e n i c

Hirsutism: Skewing of X-Chromosome Inactivation. J Clin Endocrinol Metab 1999 84(3):1091-1095

96. Wahe M, Antonipillai I, Horton R. Effects of transforming growth factor band epidermal growth factor on steroid 5areductase activity in genital skin fibroblasts. Mol Cell Endocrinol 1993 98: 55-59 97. Wilson J 1996 Androgens. In: Gilman AG, Rall TW, Nies AS, Taylor P (ed) Goodman and Gilman"s The Pharmacological Basis of Therapeutics, ed 9. McGraw Hill Publishers, New York, pp 1441-1457

98. Wudy S, Wachter U, Homoki J, Teller W. 5 alpha-androstane- 3 alpha, 17 beta-diol and 5 alpha-andostane-3 alpha, 17 beta-diol-glucuronede in plasma of anormal children, adults and patients with idiopathic hirsutism: a mass spectrometric study. Eur J Endocrinol 1996 134(1):87-92

99. Young RL, Goldzieher JW, Elkind-Hirsch K. The endocrine effects of spironolactone used as an antiandrogen. Fertil

Steril 1987 48: 223-228

ANEXOS

DESARROLLO DEL PELO

Figura 1. Desarrollo del pelo

 

Figura 2. Formación total del folículo piloso y formación del pelo

            ALTERACIONES DEL PELO

hair_05

Figura 3. Niño con Alopecia

123a047ninag

Figura 4. Niña con Hipertricosis

 

Figura 6. Alteración del folículo piloso: Tricoepitelioma múltiple (epitelioma adenoide quístico)

 

Figura 7. Alopecia andrógena: Fases de calvice.

 

 

 

 

 

Autor:

Villegas Huam?n, Yenner Antonio

javh5[arroba]hotmail.com

DOCENTES:

Dr. ?lvarez Carrillo Javier

Dr. Cruzalegui Henr?quez Rodil

Dr. Flori?n Zavaleta Luis

Dr. Fonseca Guillermo

?REA: Embriolog?a M?dica

UNIVERSIDAD NACIONAL DE TRUJILLO

FACULTAD DE MEDICINA

ESCUELA DE MEDICINA

DEPARTAMENTO DE MORFOLOG?A

FECHA: 21/07/08

Partes: 1, 2, 3, 4, 5
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