Enfermedades Cerebrovasculares e HTA: rol del tratamiento antihipertensivo crónico (página 2)

22. The ONTARGET Investigators . Telmisartan , ramipril or both in patients at high risk for vascular events . N Eng J Med 2008 ; 358:1547-59 .

23. Staessen JA , Fagard R , Lutgard T , y col for the Systolic Hypertension in Europe (Syst-Eur ) Trial Investigators : randomized double-blind comparision of placebo and active treatment for older patients with isolated systolic hypertension . Lancet 1997 , 350 :757-764 .

24. Julius S , Kieldsen SE , Weber M , et al . Outcomes in hypertensive patients at high cardiovascular risk treated with regimen based on valsartan or amlodipine : the VALUE randomized trial et al . Lancet 2004 ; 363:2022-2051 .

25. Hansson L , Zanchetti A , Carruthers SG , Dahlof B , Elmfeldt D , Menard J , et al for the HOT Study Group . Effects of intensive blood pressure lowering and low-dose aspirin in patients with hypertension : principal results of the Hypertension Optimal Trial ( HOT ) randomized trial . Lancet 1998 ; 351:1755-1762 .

26. Ghong L , Zhang W , Zhu Y , Zhu J , Kong D , Page V et al . Shangai Trial of Nifedipine in the Elderly ( STONE ) . J Hypertens 1996 ; 14:1237-1245 .

27. Tvomilehto J , Rasthyte D , Birkenhager WH . Effects of calcium-channel blockade in older patients with diabetes and systolic hypertension .N Eng J Med 1999 ; 540: 677-684.

28. Dargie H , Krumholz HM . Los betabloqueantes reducen el riesgo de mortalidad tras insuficiencia cardiaca leve . Lancet ( ed-esp ) 1999 ; 353:9-13 .

29. Lindholm LH , Carlberg B , Samuelson O . Should betablockers remain first choice in the treatment of primary hypertension ? . Lancet 2005 ; 1545-1553

30. Schiffrin E , Dey LY , Larochelle P . Progressive improvement in the estructure of resistance arteries of hypertensive patients after 2 years of treatment with an angiotensin I-converting inhibitor . Comparision with effect of a beta-blocker . Am J Hypertens 1995; 8:229-236 .

31. Waisman G , Atenolo en hypertension ¿ es una sabia eleccion ? Evid actual pract ambul 2005 ; 8:71 .

32. Psaty BM , Lumley T , Furberg CD , Schellenbaum G , Pahor M , Alderman MH , et al . Health outcomes associated with various antihypertensive therapies used as first time agents : a network meta-analysis JAMA 2003 ; 289:2534-2544 .

33. Remme WJ , Torp-Pedersen C , Cleland JGF et al . Carvedilol protects better against vascular events than metoprolol in heart failure . Results from COMET . J Am Coll Cardiol 2007 ; 49:963-971 .